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Isrib Buy. Isrib integrated stress response inhibitor. Next day delivery by 10:00 a.m.

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Next day delivery by 10:00 a.m. Products are for laboratory research use only. Isrib is a potent and selective perk inhibitor with ic50 of 5 nm.

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Isrib was found to reset the isr in the brain of old mice, through inhibitory effects on the atf4 protein. Integrated stress response (isr) is activated by diverse cellular conditions and rapidly reduces overall protein synthesis while enhancing translation of specific. Blocks atf4 production without altering the ire1 or atf6 responses in vitro. Products are for laboratory research use only.